Staptio-temporal epidemiolgy of human viruses

The immune response mounted against past and ongoing infection can leave traces in our bloodstream, such as antibodies. Serological assays can dose the presence of these antibodies specific to a specific parasite species or even genotype. We used these assays in the context of our PAPCLEAR study to monitor the immune response. Thanks to a collaboration with CERBA laboratories and French public hospital virology departments, we can anlyse a database of serological assays against human herpesviruses.

We develop statistical epidemiology models to analyse the past spread and current prevalence of 8 main human herpesviruses in France. This raises statistical hurdles associated with the spaital and temporal structure of the data.